Xeljanz/Xeljanz XR is a drug that can ease the symptoms of inflammatory diseases such as rheumatoid arthritis. It is also approved for the treatment of psoriatic arthritis and ulcerative colitis.
The FDA approved Xeljanz for rheumatoid arthritis in 2012. At the time of initial approval, the FDA required the manufacturer, Pfizer, to conduct a randomized safety clinical trial to study the risk of heart-related events and cancer. Based on the results of this trial, the FDA has concluded that there is an increased risk of serious heart-related events such as heart attack, stroke, cancer, blood clots, and death with the use of Xeljanz/Xeljanz XR.
Patients taking Xeljanz/Xeljanz XR should seek immediate medical attention if PE symptoms or other unusual symptoms occur, including:
Warning Signs of a Pulmonary Embolism:
Coughing up blood
Skin that is clammy or bluish-colored
Sudden difficulty breathing
Shortness of breath
Pain in chest or back
Warning Signs of a Heart Attack:
Discomfort in other areas body
Shortness of breath
Warning Signs of a Stroke:
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